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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NRD1
All Species:
29.39
Human Site:
Y514
Identified Species:
53.89
UniProt:
O43847
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43847
NP_001095132.1
1150
131572
Y514
I
T
L
T
D
E
G
Y
E
H
F
Y
E
V
A
Chimpanzee
Pan troglodytes
XP_001140946
1151
131624
Y515
I
T
L
T
D
E
G
Y
E
H
F
Y
E
V
A
Rhesus Macaque
Macaca mulatta
XP_001105075
1237
141727
Y601
I
T
L
T
D
E
G
Y
E
H
F
Y
E
V
A
Dog
Lupus familis
XP_859649
1159
132371
Y524
I
T
L
T
D
E
G
Y
E
H
F
Y
E
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHG1
1161
132873
Y526
I
T
L
T
D
E
G
Y
E
H
F
Y
E
V
A
Rat
Rattus norvegicus
P47245
1161
132957
Y526
I
T
L
T
D
E
G
Y
E
H
F
Y
E
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509651
859
96644
E277
G
S
L
K
Y
P
D
E
N
G
F
D
A
F
L
Chicken
Gallus gallus
NP_001026455
1158
132212
Y522
V
T
L
T
D
E
G
Y
K
H
F
Y
E
V
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694205
1091
124552
V460
F
Y
E
V
A
H
L
V
F
Q
Y
L
K
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22817
990
113666
T408
E
Q
P
E
N
L
V
T
H
A
V
S
S
M
Q
Honey Bee
Apis mellifera
XP_624437
1061
122950
H470
L
M
L
T
E
Q
G
H
K
H
L
P
E
V
L
Nematode Worm
Caenorhab. elegans
Q10040
856
98243
T274
E
I
V
P
I
Q
N
T
G
Q
V
S
I
K
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06010
1027
117560
S445
G
S
P
S
S
T
V
S
S
L
A
K
C
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
84.3
94.1
N.A.
92.4
92.3
N.A.
47.4
76
N.A.
68.3
N.A.
29.1
38.7
25.1
N.A.
Protein Similarity:
100
99.8
85.9
96.7
N.A.
95.2
95.1
N.A.
54.6
85.7
N.A.
81.9
N.A.
47.8
58.8
42.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
86.6
N.A.
0
N.A.
0
40
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
20
N.A.
13.3
73.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
8
8
0
8
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
54
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
16
0
8
8
8
54
0
8
47
0
0
0
62
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
62
0
0
8
8
% F
% Gly:
16
0
0
0
0
0
62
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
8
62
0
0
0
0
0
% H
% Ile:
47
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
16
0
0
8
8
8
0
% K
% Leu:
8
0
70
0
0
8
8
0
0
8
8
8
0
8
24
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
16
8
0
8
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
16
0
0
0
16
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
8
8
0
0
8
8
0
0
16
8
0
0
% S
% Thr:
0
54
0
62
0
8
0
16
0
0
0
0
0
0
0
% T
% Val:
8
0
8
8
0
0
16
8
0
0
16
0
0
62
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
54
0
0
8
54
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _